Cytochrome Systems: from Discovery to Present Developments.- I. Genetics.- Genetics of E.Coli Cytochromes which are Components of the Aerobic Respiratory Chain.- Molecular Genetic Approaches to Studying the Structure and Function of the Cytochrome c2 and the Cytochrome bc1 Complex from Rhodobacter Capsulatus.- Structural Homologies in the Cytochrome B/C1 Complex from Rhodobacter.- Genes and Sequences for Subunits of Respiratory Complexes in Paracoccus denitrificans.- Organization and Expression of Nuclear Genes for Yeast Cytochrome c Oxidase.- The cDNA a Structural Gene for Rat Liver Cytochrome c Oxidase Subunit Vic.- Genetics of Yeast Coenzyme QH2-Cytochrome c Reductase.- Sequence Analysis of Mammalian Cytochrome b Mutants.- Plant Mitochondrial Genes, Cytochrome c Oxidase and Cytoplasmic Male Sterility.- A Mutation Affecting Lariat Formation, but not Splicing of a Yeast Mitochondrial Group II Intron.- The Evolution of Mitochondrially Coded Cytochrome Genes: A Quantitative Estimate.- Involvement of Nuclear Genes in Splicing of the Mitochondrial COB Transcript in S. Cerevisiae.- Introns as Key Elements in the Evolution of Mitochondrial Genomes in Lower Eukaryotes.- GENETICS: Short Reports.- Core Protein Deficiency in Complex III of the Respiratory Chain, in a Missence Exonic Mitochondrial Yeast Mutant of Cytochrome b Gene.- Localization and Partial Sequencing Analysis of Mitochondrial Gene for Apocytochrome b in Sunflower.- Molecular Basis for Resistance to Inhibitors of the Mitochondrial Ubiquinol-Cytochromec Reductase in Saccharmoyces Cerevisiae.- Structure of the Proteins and Genes for the Nuclear-Encoded Subunits of N. Crassa Cytochrome Oxidase.- Partial Sequence of Gene for Cytochrome Oxydase Subunit II of Sunflower Mitochondrial DNA.- Unusual Features of Kinetoplast DNA from Trypanosomes: Novel Mechanism of Gene Expression (RNA-Editing), the Absence of tRNA Genes and the Variable Presence of a Cytochrome Oxidase Subunit Gene.- II. Biosynthesis.- Heterogeneous Efficiencies of mRNA Translation in Human Mitochondria.- Regulation of the Expression of COI and COIII mRNAs in Rat Liver Mitochondria.- Two Consensus Sequences for RNA Processing in Neurospora Crassa Mitochondria.- Primary Structure of the Yeast Nuclear CBS 1 Gene Product, Necessary to Activate Translation of Mitochondrial COB mRNA.- A Calmodulin-Like Protein in the Cytochrome bc1 Complex Required for Synthesis of Both Cytochrome bc1 and Cytochrome c Oxidase Complexes in Yeast Mitochondria.- Import of Cytochromes b2 and c1 into Mitochondria is Dependent on Both Membrane Potential and Nucleoside Triphosphates.- NADH: A Common Requirement for the Import and Maturation of Cytochromes c and c1.- Import of Proteins into Mitochondria: Structural and Functional Role of the Prepeptide.- Interaction of the Mitochondrial Precursor Protein Apocytochrome c with Model Membranes and its Implications for Protein Translocation.- Influence of Thyroid Hormones on the Expression of Nuclear Genes Encoding Subunits of the Cytochrome bc1 Complex.- II. BIOSYNTHESIS: Short Report.- Import of Cytochrome c1 and Cytochrome b2 into Mitochondria.- III. Protein Structure.- Cytochrome c Oxidase: Past, Present and Future.- Universal Features in Cytochrome Oxidase.- Polypeptide Subunits Encoded by Nuclear Genes are Essential Components of Eukaryotic Cytochrome c Oxidase.- Respiratory Complex IV and Cytochrome a,a3.- An Amino Acid Sequence Region of Subunit II of Cytochrome Oxidase which may be Responsible for Evolutionary Changes in Reactivity with Different Cytochromes c.- Evidence for a Functional Role of Nuclear Encoded Subunits in Mitochondrial Cytochrome c Oxidase.- Structural Analysis of the bc1 Complex from Beef Heart Mitochondria by the Sided Hydropathy Plot and by Comparison with Other bc1 Complexes.- Crystallisation of Water-Soluble Preparations of the Iron- Sulfur-Protein and Cytochrome c1 of Ubiquinol: Cytochrome Reductase from NeurosporaMitochondria.- Iron Cluster Sites of Cardiac Ip-Subunit of Succinate Dehydrogenase.- Polypeptides in Mitochondrial Electron-Transfer Complexes.- The Fatty Acid-Anchored Four Heme Cytochrome of the Photo- synthetic Reaction Center from the Purple Bacterium Rhodopseudomonas Viridis.- III. PROTEIN STRUCTURE: Short Reports.- Membrane Protein in Paracoccus Denitrificans Resembles Subunit III of Beef Heart Cytochrome Oxidase.- The Circular Dichroism Properties of the Rieske Protein and the b and c1 Cytochromes of the Mitochondrial bc1 Complex.- Monomerization of Cytochrome Oxidase Might Be Essential for Subunit III Removal.- Fourier-Transform Infra-Red Studies of Cytochrome c Oxidase.- Isoenzymes of Human Cytochrome c Oxidase.- Folding of Integral Membrane Proteins: Renaturation Experiments with Bacteriorhodospin Support a Two-Stage Mechanism.- IV. Reaction Domains and Oxido-Reduction Mechanisms.- The Nature of Ferryl, Fe(IV)=0, Haem in Peroxidases.- Polarization in Heme Proteins and Cytochrome c Oxidase.- Effects of Freezing on the Coordination State and Ligand Orientation in Hemoproteins.- Catalytic Mechanism of O2 Reduction by Cytochrome Oxidase.- The Electron-Transfer Reactions in and Substrate Binding to Cytochrome c Oxidase.- Control of Cytochrome Oxidase in Proteoliposomes: Flux and Stoichiometry.- Cytochrome c Oxidase Activity is Regulated by Nucleotides and Anions.- Cytochrome Oxidase and Neuromuscular Diseases.- Electron Transfer Between Cardiac Cytochrome c1 and c.- Heme Cluster Structures and Electron Transfer in Multiheme Cytochromes C3.- IV. REACTION DOMAINS AND OXIDO-REDUCTION MECHANISMS: Short Reports.- Electron Exchange Between Cytochromes a.- Pulsed, Resting and Peroxy Forms of Cytochrome Oxidase.- Effect of pH and Temperature on Electron Transfer in Mixed-Valence Cytochrome c Oxidase.- The pH-Dependence of the Reductional Levels of Cytochrome c and Cytochrome a During Turnover of Cytochrome c Oxidase.- V. Fe-S Centers.- Studies of Bacterial NADH-Ubiquinone (or Menaquinone) Oxidoreductase Systems.- Localized Valence States in Iron-Sulfur Clusters and Their Possible Relationship to the Ability of Iron-Sulfur Clusters to Catalyze Reactions Other Than Electron Transfer.- Probing the Fe/S Domain With EPR: Pandora’s BOX Ajar.- Aspects of Spin Coupling Between Even and Odd Electron Systems: Applications to Succinate: Q Reductase.- The Iron-Sulfur Clusters in Succinate Dehydrogenase.- Mechanisms of Electron Transfer in Succinate Dehydrogenase and Fumarate Reductase: Possible Functions for Iron-Sulphur Centre 2 and Cytochrome b.- VI. Quinone Binding Sites: Structure and Function.- Structural and Mechanistic Aspects of the Quinone Binding Sites of the bc Complexes.- QP-S-The Electron Acceptor of Succinate Dehydrogenase.- Characteristics of QP-C and Reconstitution of the QH2-Cyt c reductase.- The Kinetics of Oxidation of Cytochrome b are in Agreement with the Q-Cycle Hypothesis.- The Q-Reaction Domains of Mitochondrial QH2: Cytochrome c Oxidoreductase.- EPR Studies of the Quinone Reaction Sites in Bacteria.- EPR Signal II in Photosystem II: Redox and Paramagnetic Interactions with the O2 Evolving Enzyme.- Studies on the Ubiquinone Pool in Mitochondrial Electron Transfer.- VI. Quinone Binding Sites: Structure and Function: Short Reports.- Effects of Proteolytic Digestion and Chemical Modification of b-c Complex on the Fe-S Center and the Stable Ubisemi-quinone (SQc).- Kinetics of Ubiquinol Cytochrome c Reductase: Lack of a Diffusion-Limited Step with Short Chain Ubiquinols as Substrates.- VII. Specific Redox Systems.- Biochemistry and Molecular Biology of the Escherichia Coli Aerobic Respiratory Chain.- The Interplay Between Photosynthesis and Respiration in Facultative Anoxygenic Phototrophic Bacteria.- The Ubiquinol-Cytochrome c Oxidoreductase of Phototrophic Bacteria.- The Redox Reaction Between Cytochrome bH and the Semiquinone-Quinol Couple of Qc is Electrogenic in Ubiquinol-Cyt c2 Oxidoreductase.- Construction and Characterization of Monolayer Films of the Reaction Center Cytochrome-c Protein from Rhodopseudomonas Viridis.- Structure-Function Relationships in the Rhodopseudomonas Viridis Reaction Center Complex: Electrogenic Steps Contributing to ?? Formation.- Catalytic Sites for Reduction and Oxidation of Quinones.- Studies of the Electrogenicity of the Reduction of Cytochrome b561 through the Antimycin-Sensitive Site of the Ubiquinol-Cytochrome c2 Oxidoreductase Complex of Rhodobacter Sphaeroides.- Mutants Affecting the Quinol Oxidation Site of Ubiquinol-Cyt c2 Oxidoreductase.- Cytochrome b558 of Bacillus Subtilis.- Mitochondrial Cytochrome b560.- Isolation of the Photosystem Two Reaction Centre and the location and Function of Cytochrome.- VII. SPECIFIC REDOX SYSTEMS: Short Reports.- Effect of Antimycin on the Kinetics of Reduction of b and c1 Cytochromes in Single Turnover of the Mitochondrial b-c1 Complex.- The b-Q Cycle, a new model for the Pathways of Electrons and Protons through the bc1 Complex I Action of Antimycin A at Center O.- Rapid Oxidation Kinetics of Quinol Cytochrome c Oxidoreductase: Quinone or Semiquinone Cycle?.- Electron Conduction Between b Cytochromes of the Mitochondrial Respiratory Chain in the Presence of Antimycin plus Myxothiazol.- The Release of NAD Radical is the Limiting Step in the Redox Reaction Between Fe(III) Cytochrome c and NADH.- Properties of Cytochrome b558 in Complex II of Ascaris Muscle Mitochondria and its Function in Anaerobic Respiration.- VIII. Cooperativity and Allosteric Transitions.- Pulsed and Resting Cytochrome Oxidase: an Update of Optical and Molecular Properties.- Is H2O2 Involved in Electron Transport Between Cytochromes a and a3 in Cytochrome Oxidase?.- Conformational Transitions of Cytochrome c Oxidase Induced by Partial Reduction.- Redox-Linked Conformational Changes in Cytochrome c Oxidase.- IX. Proton-Motive Activity.- Protonmotive Activity of the Cytochrome Chain of Mitochondria: Models and Features.- The Mechanism of Electron Gating in Cytochrome c Oxidase.- Proton Pump Activity in Bacterial Cytochrome Oxidases.- Topography and Protonmotive Mechanism of Mitochondrial Coupling Site 2.- The Q-Gated Proton Pump Model of Ubiquinol Cytochrome c Reductase: Electron and Proton Transfer Pathways and Role of Polypeptides.- Photosynthetic Control and ATP/Electron Ratio in Bacterial Photophosphorylation.- IX. PROTON-MOTIVE ACTIVITY: Short Report.- Protonmotive Activity of Mitochondrial Cytochrome c Oxidase.- Proposal for a Novel Nomenclature for the Subunits of Cytochrome c Oxidase G. Buse, G.C.M. Steffens, R. Biewald, B. Bruch and S. Hensel.- Author Index.