Epigenetic Regulation of Lymphocyte Development

Paperback Engels 2014 2012e druk 9783642447679
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Samenvatting

The studies described in this volume serve as a starting point to familiarize one self with the multifarious differences in epigenetic designs that orchestrate the progression of developing blood cells. They also may serve as a general paradigm for the mechanisms that underpin the control of eukaryotic gene expression. 

Specificaties

ISBN13:9783642447679
Taal:Engels
Bindwijze:paperback
Aantal pagina's:194
Uitgever:Springer Berlin Heidelberg
Druk:2012

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Inhoudsopgave

<p>Preface.- Roles of lineage-determining transcription factors in establishing open chromatin – lessons from high-throughput studies.- B Lymphocyte Lineage Specification, Commitment and Epigenetic Control of Transcription by Early B Cell Factor 1.- Epigenetic features that regulate IgH locus recombination and expression.- Local and global epigenetic regulation of V(D)J recombination.- Genetic and Epigenetic Regulation of TCRbeta Gene Assembly.- T-cell identity and epigenetic memory.- Encoding stability versus flexibility:  Lessons learned from examining epigenetics in T helper cell differentiation.- The epigenetic landscape of lineage choice: lessons from the heritability of Cd4 and Cd8 expression.-  Subject Index</p>

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        Epigenetic Regulation of Lymphocyte Development